Pregnancies are Critical by Preterm Birth or Pre-eclampsia

Circulating foetal DNA factors an inflammatory response that gives you impulsive preterm birth, in accordance with new research from Trinity Biomedical Sciences Institute at Trinity College Dublin as well as the Coombe Women and Infants University Hospital.

The breakthrough just published within the Journal of Immunology has proved that in fact mothers whose pregnancies are complex by preterm birth or pre-eclampsia have higher levels of a typical baby’s DNA with their blood.

The scientists have proved the fact that DNA is sensed by the protein known as Toll-like receptor-9 (TLR9), which generally provokes an inflammatory reaction which results in pregnancy loss and early delivery.

However, the Irish research has revealed that this result might be blocked by drugs that concentrate on TLR9. They say that their own data presents a novel mechanism for preterm birth and pre-eclampsia, potentially creating TLR9 as a potential therapeutic target for the following common problems of being pregnant.