Tuesday 17 January 2012

Will New Approach Reduce The Side Effects Of Clinical Trials Before They Pass to Clinical Trial?


Drug formulation by the expert researchers is followed by clinical trial before it hits the market. The side effects of the drug are finding an easy way into the clinical trials due the existing practices and millions of dollars are being wasted due to the failures in the clinical trials. The newly formulated drugs are tested on the mice to know the side effects before they are passed into the clinical trials. As the functionality of the mice liver differs from that of humans, they react differently and the side effects are finding an easy way into humanized clinical trials. 

The new innovation broke the ice at this juncture. Effort from the expert researchers enabled them to send the human liver cells into the mice, therefore developing humanized mice which could react like humans when the drugs are experimented. The process requires number of mice to conduct the process which is again a challenge here. The idea to reduce the side effects in the drug before it passes to the clinical trial sounds very valuable. The idea would also sound practically good if the researchers can develop the capability of inducing hundreds and thousands of implants in mouse.

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